Chromosome substitution strains
WebA chromosome substitution strain (CSS) or consomic strain is an inbred strain in which a single chromosome from a donor strain replaces the corresponding chromosome in … WebA chromosome substitution strain (CSS) or consomic strain is an inbred strain in which a single chromosome from a donor strain replaces the corresponding chromosome in the host/parental strain on a defined and uniform genetic background. From:Handbook of Behavioral Neuroscience, 2016 Related terms: Phenotype Mutation Quantitative Trait Locus
Chromosome substitution strains
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WebSep 29, 2024 · Analyzing metabolic traits and gene expression levels in the offspring of a series of crosses between mouse chromosome substitution strains demonstrated that inter-chromosomal epistasis was a dominant feature of these complex traits. Epistasis typically accounted for a larger proportion of the heritable effects than those due solely to … WebMar 28, 2024 · 5.3 Chromosome Substitution or Consomic Strains 5.3.1 Consomic Strains 5.4 Segregating Inbred Strains 5.5 Conplastic Strains 6. Outbreds and Closed Colonies 6.1 Outbreds 6.2 Closed Colonies 7. ES cell lines and iPS cell lines 8. References 1. Introduction Mice and rats used in the laboratory derive from a variety of sources.
WebChromosome substitution strains QTL mapping can be accelerated using chromosome substitution strains (CSSs), which enable the first two steps above to be omitted. We … WebGenetic crosses and chromosome substitution experiments conclusively showed that the expression of both genes (located on the 2R chromosome) is repressed by factors on the third chromosome of the insecticide-susceptible 91C and rosy 506 strains. In contrast, the third chromosome of the MHIII-D23 and 91R strains carries a loss-of-function ...
WebRecombinant inbred (RI) and chromosome substitution (CS) strain panels Many common inherited human diseases — such as diabetes, cardiovascular disease, obesity, … http://informatics.jax.org/nomen/strains.shtml
WebChromosome substitution strains (CSSs) are important in this resource portfolio because of their demonstrated use for gene discovery, genetic and epigenetic …
WebJun 12, 2006 · An analysis of transcriptional variation in the liver using a panel of B.A chromosome substitution strains identified 4209 transcripts that are differentially expressed relative to the C57BL/6J background and 1010 transcripts that are differentially expressed between C57BL/6J and A/J strains. A subset of these strains (substituting … genius childcare youtubeWebApr 16, 2004 · Chromosome substitution strains (CSSs) have been proposed as a simple and powerful way to identify quantitative trait loci (QTLs) affecting developmental, … chown group ownerWebChromosome substitution strains (CSSs) are based on a different paradigm that deal with the signal-noise problem in a novel way . Each CSSs is an inbred strain that differs from … chown hardware portland orWebGenetic crosses and chromosome substitution experiments conclusively showed that the expression of both genes (located on the 2R chromosome) is repressed by factors on the third chromosome of the insecticide-susceptible 91C and rosy506 strains. chown hardware catalogWebMay 23, 2024 · chromosome substitution The replacement of one or more chromosomes by others (totally or partially homologous) from another source (either a different strain of the same species or a related species that will permit hybridization) by a suitable crossing programme. A Dictionary of Zoology MICHAEL ALLABY chown hardware bellevue washingtonWebJul 8, 2003 · A chromosome substitution strain (CSS) is an inbred strain in which one chromosome has been substi-tuted from a different inbred strain by repeated backcrossing. A complete CSS set has one strain representing each chromosome against a uniform background, thus allowing genome-wide scans to be carried out for … chown helpWebJun 29, 2016 · Selecting chromosome substitution strains (CSSs, also called consomic strains/lines) used in the search for quantitative trait loci (QTLs) consistently requires the identification of the respective phenotypic trait of interest and is simply based on a significant difference between a consomic and host strain. However, statistical significance as … chown hardware reviews