Cisplatin diabetes

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August undefined, 2024

WebMar 1, 2024 · Cisplatin is a well‐known chemotherapeutic agent that can be associated with hyponatremia. It is known to be associated with a multitude of renal disorders including acute kidney injury with reduced glomerular filtration, Fanconi syndrome, and renal tubular acidosis, nephrogenic diabetes insipidus and renal salt wasting syndrome. WebThey include 5-fluorouracil (5-FU)-based chemotherapy, asparaginase (Elspar), busulfan (Busulfex, Myleran), and platinum-based chemotherapy, such as cisplatin (Platinol). …

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WebAgeing kidney; cardiovascular disease; cisplatin nephrotoxicity; diabetes mellitus; lung cancer; High-dose cisplatin (Cp)-based combination chemotherapy regimens are used as front-line treatments of nonsmall cell and small cell lung cancer 1.The therapeutic effects of Cp are significantly improved by dose escalation. WebApr 10, 2024 · Systemic therapy is considered standard of care for previously untreated BTC and often includes gemcitabine and cisplatin chemotherapy as established by the phase III ABC-02 trial. 7 A phase ... Comorbidity status was collected for diabetes, hypertension, dyslipidemia, chronic kidney disease, and CVD. The latter included arrhythmias ... small cap wealth

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WebFeb 26, 2024 · severe or ongoing nausea and vomiting; vision problems, pain behind your eyes; hearing problems, ringing in your ears; pain, redness, swelling, or skin changes where the injection was given; bone ... WebApr 4, 2024 · Common carboplatin side effects may include: low blood cell counts; loss of appetite; nausea, vomiting, diarrhea; numbness, burning pain, or tingly feeling; temporary hair loss; or. pain in your hands or feet. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. WebSep 1, 2024 · Improving Ototoxicity Monitoring with Cisplatin Therapy at VA Northeast Ohio Healthcare System (VANOHS), An Interdisciplinary Team Approach somerset care nursing homes

Clinical Challenges in Caring for Patients With Diabetes …

Cisplatin and Diabetes for Oral Cancer treatment VoCP

WebFeb 21, 2024 · Our data show that the usage of DPP-4 inhibitors to diabetic-cancer patients could reduce the incidence of cisplatin-induced AKI from 64% to 25%, but its preventive … WebDec 3, 2024 · Cisplatin-based chemotherapy (CBCT) is part of standard treatment of several cancers. In testicular cancer (TC) survivors, an increased risk of developing metabolic syndrome (MetS) is observed. In this epigenome-wide association study, we investigated if CBCT relates to epigenetic changes (DNA methylation) and if epigenetic … small cap vs mid cap performanceWebSep 1, 2024 · Cisplatin, the active ingredient in Cisplatin for injection, USP, is a yellow to orange crystalline powder with the molecular formulaCl 2 H 6 N 2 Pt and a molecular weight of 300.05. Cisplatin is a heavy metal complex containing a central atom of platinum surrounded by two chloride atoms and two ammonia molecules in the cis position. small cap weed stocks

"WebMay 18, 2024 · The high incidence of cisplatin-induced nephrotoxicity in elderly patients may be associated with renal hypoperfusion; increased comorbidities, such as chronic kidney disease (CKD), cardiovascular disease, and diabetes mellitus; increased use of combined drugs [especially non-steroidal anti-inflammatory drugs, angiotensin … " - Cisplatin diabetes

Cisplatin diabetes

WebFeb 1, 2024 · Call your doctor right away if you have a rash, diarrhea, a fever or chills, hives, hoarseness, itching, lightheadedness or dizziness, trouble breathing, trouble swallowing, … WebAug 14, 2024 · In the literature, some of the studies suggested that diabetes and/or coronary artery diseases pose a risk for cisplatin-induced nephrotoxicity [ 6, 8, 19, 20 ]. Diabetes mellitus and coronary artery disease may increase the incidence of cisplatin-induced nephrotoxicity by increasing atherosclerosis and associated glomerulosclerosis [ …

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WebFeb 1, 2016 · There are a lot of causes for water and electrolytic disturbances and, among them, transient diabetes insipidus (DI) has been found to be the most common followed by syndrome of inappropriate... WebFeb 1, 2016 · Request PDF Central Diabetes Insipidus and Cisplatin-Induced Renal Salt Wasting Syndrome: A Challenging Combination We describe a 2-year-old female with …

WebMar 2, 2024 · Cisplatin is a potent anticancer drug widely used for the treatment of several malignant tumors. One of the most relevant side effects of cisplatin is nephrotoxicity, that is very well-known since its introduction in 1978 and limits its use and efficacy [ 1, 2 ]. WebApr 1, 2013 · Pathophysiology of Diabetes Insipidus (DI) DI is a clinical syndrome characterized by polyuria (due to a defect in the urinary concentrating mechanism) and compensatory polydipsia. In the general population, the prevalence of DI is approximately one per 25,000–30,000 ( 7 – 9 ).

WebElectrolyte disturbance: Cisplatin can cause hypomagnesaemia, hypokalaemia and hypocalcaemia. The hypocalcaemia seems to occur in those with low serum magnesium secondary to cisplatin, so it is not … WebCisplatin is a chemotherapy drug that is used to treat many different types of cancer. It works by damaging the DNA in cancer cells and stopping them from multiplying. It binds together the strands of the DNA so that the cells cannot grow a .. More information can be found on cancerresearchuk.org andcancer.gov

Web17 hours ago · Injectable cisplatin, methotrexate, and fluorouracil These generic drugs are widely used to treat common cancers in adults and children. Methotrexate treats acute lymphoblastic leukemia in...

WebJul 1, 2006 · Cisplatin, paclitaxel, and vincristine may be neurotoxic. Unfortunately, many of these side effects from chemotherapeutic agents are permanent. Successful cancer … somerset car show 2022 somerset ca weatherWebDec 16, 2024 · Cisplatin (CDDP; cis-dichlorodiammine platinum [II]) is a non-specific drug of the cell cycle with strong cytotoxicity and broad-spectrum antitumor effects; it is widely used in urogenital system tumors, malignant lymphoma, breast cancer, head and neck cancer, non-small cell lung cancer, etc. ( 1 – 3) Cisplatin-induced nephrotoxicity is … small cap wind stocksWebFeb 1, 2003 · Cisplatin, a heavy metal coordination compound that induces apoptosis of cancer cells, is widely used in a variety of cancers. Cisplatin treatment induced transient … somerset carpet cleaningWebCisplatin and Diabetes Cisplatin is a chemotherapy drug that is used to treat many different types of cancer. It works by damaging the DNA in cancer cells and stopping … small cap wigsWebSep 15, 2024 · Cisplatin Injection (cisplatin injection (cisplatin (cisplatin injection) injection) ) is a sterile aqueous solution, available in 50, 100 and 200 mL multiple dose … small cap winnersWebOct 6, 2016 · Cisplatin [Cis-diamminedichloroplatinum(II)] is the most nephrotoxic chemotherapeutic drug, discovered over four decades ago. Nephrotoxicity is the major side effect that limits the dose of cisplatin that can be safely administered, and it is a clinical problem in cancer patients who receive cisplatin combination chemotherapy. somerset catch fish and chips