Glial fibrillary acid protein
WebApr 23, 2013 · The brain-specific astroglial protein GFAP is a blood biomarker candidate indicative of intracerebral hemorrhage in patients with symptoms suspicious of acute stroke. Comparably little, however, is known about GFAP release in … WebGlial Fibrillary Acidic Protein Human ELISA (GFAP) Regulatory status: RUO Type: Sandwich ELISA, Biotin-labelled antibody Other names: GFAP Species: Human Please select your region to see available products and prices. PubMed Product Details Technical Data Type Sandwich ELISA, Biotin-labelled antibody Applications
Glial fibrillary acid protein
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WebGlial fibrillary acidic protein (GFAP) is an intermediate-filament (IF) protein that is highly specific for cells of astroglial lineage, although its tissue-specific role is speculative. Determination of the primary structure of this protein should be of importance for understanding the functional role it plays in astroglia. Glial fibrillary acidic protein (GFAP) is a protein that is encoded by the GFAP gene in humans. It is a type III intermediate filament (IF) protein that is expressed by numerous cell types of the central nervous system (CNS), including astrocytes and ependymal cells during development. GFAP has also been found … See more Type III intermediate filaments contain three domains, named the head, rod and tail domains. The specific DNA sequence for the rod domain may differ between different type III intermediate filaments, but the structure of the See more There are multiple disorders associated with improper GFAP regulation, and injury can cause glial cells to react in detrimental ways. Glial scarring is a consequence of several See more Although GFAP alpha is the only isoform which is able to assemble homomerically, GFAP has 8 different isoforms which label distinct … See more • Cáceres-Marzal C, Vaquerizo J, Galán E, Fernández S (October 2006). "Early mitochondrial dysfunction in an infant with Alexander … See more GFAP is expressed in the central nervous system in astrocyte cells, and the concentration of GFAP differs between different regions in the See more Glial fibrillary acidic protein has been shown to interact with MEN1 and PSEN1. See more • 17q21.31 microdeletion syndrome (Koolen–de Vries syndrome) • GFAP stain See more
WebDec 10, 2024 · Glial fibrillary acidic protein (GFAP) autoimmune astrocytopathy is characterized by GFAP autoantibody positive encephalitis, meningoencephalitis or meningoencephalomyelitis. The initial clinical presentation may be similar to central nervous system infections making early diagnosis challenging. Case presentation
WebMay 12, 2016 · Metrics. Glial fibrillary acidic protein (GFAP) is the main component of intermediate filaments of the cytoskeleton of astrocytes. Over more than four decades of fundamental and applied studies, GFAP achieved the status of the classical marker for astroglia. Our review deals with the analysis and systematization of the literature data ... WebJun 1, 2024 · Glial fibrillary acid protein (GFAP) (Madeddu et al., 2013), a monomer intermediate filament protein 8 ∼ 9 nm in length that is expressed only in mature astrocytes in the central nervous system, can be spontaneously degraded in vivo and in vitro. GFAP is a hallmark of reactive hyperplasia of astrocytes following brain injury and a ...
WebOct 22, 2016 · GFAP glial fibrillary acidic protein Gene ID: 2670, updated on 29-Mar-2024 Gene type: protein coding Also known as: ALXDRD See all available tests in GTR for …
WebGlial Fibrillary Acidic Protein Immunostain, Technical Component Only Useful For Classification of glial tumors Reflex Tests Testing Algorithm For the initial technical … essai fz8 2011WebJul 14, 2024 · PubMed Abstract: Glial fibrillary acidic protein (GFAP) is a homopolymeric type III intermediate filament (IF) that plays essential roles in cell migration, mitosis, development, and signaling in astrocytes and a specific type of glial cells. Its overexpression and genetic mutations lead to abnormal IF networks and accumulation of Rosenthal ... hba distributionWebIf a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance or the concentration of the product. Glial fibrillary acidic protein/GFAP Monoclonal antibody specifically detects Glial fibrillary acidic protein/GFAP in Human samples. It is validated for Immunoblot, Immunohistochemistry ... hba diplomaWebOct 19, 2024 · It is known that GFAP is an intracellular protein that forms an integral component of astrocyte cytoskeletons and also plays a pivotal role in multiple astrocytic … hba diabetesWebGlial Fibrillary Acidic Protein (GFAP) 胶质纤维酸性蛋白（GFAP）是分子量为52KD的中间丝蛋白，据报导表达在胶质细胞，如星形胶质细胞和室管膜细胞中。. 在外周神经系统中，GFAP表达在雪旺氏细胞，肠道的胶质细胞和人的感觉神经中枢卫星细胞。. 在肿瘤组织 … hba distribution keadyWebJan 25, 2024 · Glial fibrillary acid protein (GFAP) is a commonly used target for immunohistochemistry and is positive in many glial cells and tumors of glial origin. … hba design hiringWebJul 14, 2024 · PubMed Abstract: Glial fibrillary acidic protein (GFAP) is a homopolymeric type III intermediate filament (IF) that plays essential roles in cell migration, mitosis, … essai fz8 2012